Scientists have known for some time that cannabinoids can stimulate bone formation and inhibit bone loss, and researchers in Israel may now be paving the way for future cannabinoid drugs aimed at treating osteoporosis and other degenerative skeletal conditions.
Investigators at the Hebrew University Bone Laboratory assessed the ability of CBD administration to promote healing in rats with mid-femoral fractures. Researchers reported, “CBD markedly enhanced the biomechanical properties of the healing femora after 8 weeks.”
Authors also evaluated the administration of THC and CBD together, but reported that this combined preparation was “not advantageous” over CBD alone.
Their conclusion was that “CBD alone is sufficiently effective in enhancing fracture healing. … Multiple experimental and clinical trials have portrayed CBD as a safe agent suggesting further studies in humans to assess its usefulness for improving fracture healing.”
- Study Overview– Cannabidiol, a Major Non-Psychotrophic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts.